About Hyaluronidase | Filler Dissolver

Hyaluronidase, also known as filler dissolver or filler reversal, is a procedure that involves the enzyme called hyaluronidase to break down and dissolve previously injected dermal fillers. This is typically done in cases where a patient is unhappy with the results of their filler treatment, experiences complications, or wishes to make adjustments.  Hyaluronic acid-based dermal fillers, such as those used for lip augmentation, wrinkle reduction, or facial contouring, can be effectively dissolved using hyaluronidase. 

Hyaluronidase is an enzyme that naturally occurs in the body and is used in medical settings to help disperse and break down hyaluronic acid-based substances. The process of dissolving dermal filler involves injecting hyaluronidase into the treated area, which begins to break down the hyaluronic acid filler material. This allows for the filler to be gradually absorbed by the body, leading to a reduction in volume or effects. The speed and extent of the dissolution depend on various factors, including the type and amount of filler originally injected.

Who is this for?

Male and female who is unhappy with your dermal filler results or wish to reverse facial fillers.

When it’s not suitable?

Most patients will be fine to undertake dermal fillers injection, however, in certain circumstances,  dermal fillers are not recommended:

  • If you are pregnant or breastfeeding
  • If there is active skin inflammation or infection in or near the areas  


Hyaluronidase 1500 I.U.

Best Practices


Avoid alcohol consumption before the treatment to prevent bruising.



No rubbing or massaging of the injected area for 24 hours after treatment.

No strenuous exercise and sauna for 24 hours after treatment.

Wait at least 24 hours after injection before consuming alcohol. Avoid spicy food and seafood.

Stay well hydrated by drinking water.

Frequent Questions

Hyaluronidase does not work on permanent or semi-permanent dermal fillers. i.e. Ellanse and Radiesse.

The common brands of hyaluronic acid fillers that can be dissolved are:

  • Juvederm
  • Restylane
  • Stylage
  • Belotero
  • Teosyal

The common side-effects from hyaluronidase are swelling and bruising at the injected part.

A patch test can is recommended before the procedure. The practitioner will inject a small amount of Hyaluronidase at one of your arms. You will need to wait for 30 minutes to see the results of the patch test. The common sign of allergic reaction is swelling, rash, and redness at the injected part.